Endocrine Abstracts

A 60-year-old female was referred to the department in October 2010 after a CT thorax revealed an incidental finding of a right adrenal nodule. On questioning, the patient reported some sweats but otherwise no other symptoms of hormonal excess. Adrenal functional studies were normal and it was therefore decided that the patient should have a repeat CT scan in 6 months. Repeat CT adrenal glands in April 2011 did not show any changes to the size of the nodule but gave indetermin...

Background: The majority of thyroid nodules are clinically insignificant, however considerable overlap in radiological characteristics exists for benign and malignant lesions. Recently, validated radiological criteria using thyroid imaging reporting and data system scoring (TIRADS) have shown correlation between cumulative suspicious features and risk of malignancy1.Objective: To assess sensitivity, specificity and reliability of ultrasound sc...

Aim: We performed a retrospective analysis to evaluate the surgical treatment of primary hyperparathyroidism in a tertiary referral centre.Methods: We reviewed the case notes of 80 patients who underwent parathyroid surgery (2003 to 2011). Patients were identified from the national BAETS audit.Results: Median age was 56 years (range 25–86). 72.5% of the patients were females and 30% were asymptomatic. Mean adjusted calcium con...

A 43-year-old woman presented acutely with Graves disease and hyperthyroidism. She had thyroid eye disease and a large diffuse goitre with pressure symptoms. She reported hearing a bruit herself without a stethoscope. She was tachycardic, with capillary nail fold pulsation and a positive Pemberton’s sign. Initial T4 was 78.6, TSH not detected.Betablockers to control the patients tachycardia were contraindicated due to a history of asthma,...

Use of 18F-FDG-PET/CT (PET) staging for a variety of malignancies has increased in recent years. A rise in detection of incidental thyroid lesions creates a novel diagnostic challenge. We present four cases of Thyroid PET positivity.A 62-year-old lady with pulmonary adenocarcinoma on contrast CT-Thorax had diffuse thyroid PET uptake. Biochemistry revealed a self-limiting TSH rise. Thyroid ultrasound showed benign nodular goitre (U2). Findin...

Use of 18F-FDG-PET/CT (PET) staging for a variety of malignancies has increased in recent years. A rise in detection of incidental thyroid lesions creates a novel diagnostic challenge. We present four cases of Thyroid PET positivity.A 62-year-old lady with pulmonary adenocarcinoma on contrast CT-Thorax had diffuse thyroid PET uptake. Biochemistry revealed a self-limiting TSH rise. Thyroid ultrasound showed benign nodular goitre (U2). Findin...

A 60-year-old man underwent investigations for weight loss and abdominal pain. A CT thorax/abdomen revealed a 2 cm right adrenal nodule, 3 nodules in the left adrenal all <1.4 cm and a 5 mm lung nodule in the right middle lobe. The single phase CT was unable to characterize the adrenal lesions. MRI adrenal showed solid mixed signal pattern in the nodules with signal drop off in opposed phase series consistent with adenomata. Twenty-four hour urine catecholamines, cortisol,...